Latest News of Herpes Research/Cure
I am starting this discussion for people to post any and the latest info about a possible cure for this stupid virus. I have been waiting 25 years to see it and it seems there are some promising studies trying to eradicate the viruses once and for all. One uses a method of forcing all of the virus out of dormancy in the nerve bundles to be eradicated totally by current drugs. i anyone knows of any other news or recent findings, please post them here TY~
Hello :) I recently emailed Dr. bryan cullen at duke university. He has been conducting research on herpes for some time now. He sent me a link n this is what the page says:
Thank you for your interest in our research. We continue to receive a considerable number of e-mails that have asked questions about the report we published in 2008 in the scientific journal "Nature." This report received extensive press coverage, some of it misleading. We will briefly answer some of the most common questions that we have been asked, and particularly how our work relates to a new treatment for cold sores, caused by Herpes Simplex Virus 1 (HSV-1), or genital ulcers, caused by the related but distinct HSV-2. We also attach the press release issued by Duke University Medical Center, which was the basis for all the press reports. Future updates on our research progress will be added to my website, so please check back there periodically: http://cullenlab.duhs.duke.edu/faq/. Please note that I am not a physician and am not able to answer questions or provide advice about your specific health situation. 1) What have you accomplished? Our work provides, for the first time, a molecular understanding of how HSV-1 establishes a life-long latent infection in the nerve cells of the face, and how it reactivates from latency to cause cold sores. 2) Have you developed a new treatment for cold sores? The work we have performed provides a basis for the development of anti-HSV-1 and anti-HSV-2 drugs that might be able to permanently clear these viruses from patients. 3) Are these drugs being used on people? No, but we hope to initiate trials in mice to study efficacy and toxicity in the near future. Due to limited funding, we are currently focused on providing more evidence in support of our hypothesis that viral reactivation can be regulated. 4) When might this drug reach the clinical trial stage? We anticipate several years of animal experiments in mice followed by approximately 1-2 years of toxicity studies in other animals, followed by small studies in healthy volunteers. This timeline is dependent on obtaining additional research funding, which we have not yet succeeded in doing. After that, assuming things go well, this drug might proceed to clinical trials in HSV-1 infected individuals. It is very possible that the drug candidate might fall out at any of these stages, due to lack of effectiveness or some unanticipated side effect. 5) How does this relate to HSV-2, which causes genital herpes? Most of our work so far has been on HSV-1, the cold sore virus, but HSV-2 is quite closely related. We are endeavoring to see if the lessons we have learned in HSV-1 also apply to HSV-2, and our recent results indicate that this is indeed the case (Umbach et al., Journal of Virology, 84, pp. 1189-1192, 2010). We hope to eventually start animal trials for an anti-HSV-2 drug, depending on the results with HSV-1 and our financial resources. Our initial data indicate that HSV-1 and HSV-2 may respond to distinct, but similar, drug therapies. 6) Would you be willing to accept a financial contribution to be used for your research focusing on HSV-1 and HSV-2? Funding is a major constraint on our ability to advance the research, so I am therefore pleased to tell you that the National Institutes of Health has recently awarded a five-year research grant to my laboratory and that of our collaborator Prof. David Bloom at the University of Florida, which will commence in December of this year. This is in addition to a research grant to my lab from a major pharmaceutical company to support our work on herpes that will give us $80,000 a year for two years. This is still far short of what we would need to go to clinical trials, but it is a big help. Moreover, we are very encouraged by the interest from a drug company, as any treatment that eventually emerges from our work would not be available unless it is marketed by a company. Given that pre-clinical trials are very expensive--probably >$1,000,000 would be required--it is likely that small donations, while appreciated, would only have a limited effect at this time. However, we are hopeful that additional experimental evidence further validating our model for the regulation of HSV-1 and HSV-2 latency will eventually persuade NIH, or a pharmaceutical or biotech company, to support drug discovery efforts leading to animal tests and finally, if successful, a clinical trial. Nonetheless, it still looks like it will be several years before any clinical trials will become possible. If you are interested in making a contribution, you may do so in one of the following ways: Online: https://www.gifts.duke.edu Partway down the page, you are asked to make a designation for your gift. Choose Additional/Other designations and put "Professor Bryan Cullen account 3990310" on line 1. (All gifts designated for this account must be credited to this account.) Mail: Alumni and Development Records Duke University Box 90581 Durham, NC 27708-0581 Phone: (919) 684-2338 Fax: (919) 684-8527 In the memo line of the check, please write: Professor Bryan Cullen 3990310. If have any questions, please contact: Josh Bond Director of Development Duke Global Health Institute Phone: (919) 681-7863 E-mail: firstname.lastname@example.org 7) What can I use to treat chronic HSV-1-induced cold sores or HSV-2-induced genital ulcers now? All treatment decisions should be made in consultation with your physician, and no general guidelines will apply to everybody. While there are no drugs that attack latent herpes viruses, three closely related prescription drugs (Zovirax/ acyclovir; Famvir/famciclovir and Valtrex/ valacyclovir) are potent inhibitors of active virus that work quite well for many people and that you might discuss with your physician. We hope this information answers your questions and is helpful. Please be assured that we are continuing to work on the problem of developing novel HSV-1 and HSV-2 treatment approaches. Sincerely, Bryan R. Cullen
Hope this helps!
If everyone who has herpes could just donate one dollar they'd have millions to use on this research. Think about it :)
thanks for the post!
http://www.miraclemineral.org/ check out this site, i understand u dont want to believe there has been a cure out for over 70yrs but its ok, maybe one day you can take a look at it and thank jim humble, he even has a facebook and every one around the world are talking bout almost every disease they cured i know its hard to believe but i just hope u check it out, and i agree i was the same way as you i thought there was no cures no nothing but aids is a man made virus, hiv never came from monkeys they are all cover ups to supress the citizens of america from believe there was no cure in the first place, there are proof that they made hiv / aids to reduce population since the world is over crowded, like i said it is hard to believe but we really need to open our eyes and learn the truth, my mother has hiv and hep c and she will be starting her mms soon and i promise i will keep everyone updated, i know there are alot of scams but i can tell mms is not a scam, maybe one day you will learn bout mms and decide to try it ur self, unlike medicals prescribed pills which kill over 100,ooo people every year mms has no death counts what so ever.. well im done talk for now so i hope you decide to do the right thing and many blessing's..